What is RHD?
Overview
Rheumatic Heart Disease (RHD) is a chronic heart valve condition affecting over 55 million people worldwide, with the highest burden in children and young adults in low-resource settings. It starts with untreated strep throat caused by Streptococcus pyogenes, leading to Acute Rheumatic Fever (ARF), which can cause symptoms like fever, joint pain, and involuntary movements (Sydenham chorea). Repeated ARF episodes damage the heart valves, resulting in RHD.
Key risk factors include recurrent untreated or inadequately treated strep infections. RHD can cause severe symptoms such as fatigue, chest pain, difficulty breathing, and swollen joints, with complications like stroke or heart failure. Early detection and treatment of strep throat, along with prompt RHD diagnosis and prophylaxis, can prevent this disease.
Where can I learn more about RHD?
Other Heart Diseases
At ACT, we are building a global network of clinicians, researchers, and policymakers to improve outcomes for people living with rheumatic heart disease (RHD)—but we know that care doesn’t happen in isolation. ACT can also serve as a clinical registry and tool for patients with other structural heart diseases, including acquired and congenital heart conditions. Beyond heart disease, we are actively exploring partnerships to expand ACT’s reach to other chronic non-communicable diseases that require long-term follow-up and care. By working together, we can create a more connected, comprehensive approach to patient care worldwide.